While listening I couldn't help but think it would be much easier for blind people to use a command prompt and lynx-like applications.  Perhaps money would be better spend building text based apps for whatever it is that blind folks would like.  A text based twitter client specialized for the disabled, stuff like that?

Tabbing through 2d laid out forms - is that really the best way to be doing this?

I'm not blind, but back in the day, I was able to use Windows 95 without a screen to do a few simple things, such as change screen resolution.  And it's cool that people who do this a lot get really good at it, but most people shouldn't have to install so many times that they'd get really good at using a GUI without being able to see it.

Also on indiegogo the figure of 1 billion people with disabilities is mentioned.  Are there really that many people disabled to the point where they need a special operating system?  I admire the project and its goals, but is that not overstating the problem unnecessarily? 

I apologize if this sounds harsh.  I plan on donating and wish the project luck.